NFL December 7, 2025

The Bills roll into LA riding a five-game winning streak with Josh Allen playing at an MVP level. Allen has thrown for 2,890 yards with 24 touchdowns against just 5 interceptions, and his rushing ability continues to make Buffalo's offense nearly unstoppable. The Rams need this game badly to keep their playoff hopes alive, sitting right on the bubble at 6-6.

Matthew Stafford has been solid but not spectacular, and Puka Nacua is having a monster second season with 1,150 receiving yards already. The Rams' defense has been inconsistent, ranking 18th in points allowed. Buffalo's balanced attack with James Cook emerging as a legitimate threat out of the backfield gives them multiple ways to attack. The Bills are 7-5 ATS this season and have covered in four straight road games.

This is a fascinating matchup between two teams heading in opposite directions. San Francisco has been ravaged by injuries all season but still has talent everywhere. The Bears, meanwhile, have exceeded all expectations under Ben Johnson with Caleb Williams developing into a franchise quarterback. Chicago is 8-4 and in the thick of the NFC North race.

Brock Purdy has been dealing with a shoulder issue that's affected his deep ball accuracy, though he's still completing 67% of his passes. The 49ers' run game has carried them lately with Christian McCaffrey finally healthy. Chicago's defense has been stout at home, allowing just 18.2 points per game at Soldier Field. The weather forecast calls for temperatures in the low 30s with wind gusts up to 25 mph, which could limit the passing attacks.

NFC West divisional clash with major playoff implications. The Seahawks control their own destiny at 7-5 but can't afford to slip up against Arizona. Geno Smith has thrown for over 3,000 yards and the Seattle offense has found its rhythm with DK Metcalf and Jaxon Smith-Njigba forming a deadly duo. Kenneth Walker III is healthy and running hard.

Kyler Murray has been exceptional when healthy this season, and he's putting together an MVP-caliber campaign with 3,200 passing yards and 22 touchdowns. Marvin Harrison Jr. has been everything the Cardinals hoped for, catching 72 passes for 1,050 yards. This game could come down to which defense can get stops in the fourth quarter. Seattle is 4-1 at home while Arizona has struggled on the road at 2-4.

AFC North rivalry game, though the Browns have fallen on hard times this season at 3-9. Cleveland's quarterback situation has been a mess all year, and the offense ranks dead last in the league in scoring. Pittsburgh's defense should have a field day, as T.J. Watt and the Steelers pass rush leads the NFL with 44 sacks through 12 games.

Russell Wilson has stabilized Pittsburgh's offense since taking over, and the Steelers are 7-2 in games he's started. George Pickens has been outstanding with 950 receiving yards, while Najee Harris continues to grind out tough yards. The Browns' only hope is to keep this game ugly and low-scoring. Pittsburgh is 5-1 at home and Cleveland is 1-5 on the road. The seven-point spread feels about right for this divisional mismatch.