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Guardians vs Twins Betting History
The Guardians and Twins have met 176 times in the regular season since 2016, and the Guardians lead the series 98-78. Betting the Guardians on the closing moneyline in every meeting returned +5.77u; betting the Twins returned -9.58u. The games went 67-102-7 against the total, leaning under.
Updated October 1, 2026. Closing lines, regular season meetings only, 2016 to 2026. How these numbers are calculated.
Guardians vs Twins betting summary
The moneyline favorite won 91 of 172 meetings with a clear favorite (52.9%). Betting the favorite every time returned -16.85u; betting the underdog every time returned +13.27u. The Guardians were 85-89 on the run line in the series.
Guardians vs Twins results by season
Moneyline units risk 1 unit on that team in every meeting at the closing price.
| Season | Games | Guardians record | Guardians ML units | Twins ML units | Guardians run line | O/U/P | Avg total | Avg runs |
|---|---|---|---|---|---|---|---|---|
| 2026 | 13 | 6-7 | -1.87u | +1.35u | 7-6 | 6-7-0 | 7.92 | 8.69 |
| 2025 | 13 | 9-4 | +4.19u | -4.87u | 4-7 | 4-8-1 | 7.88 | 7.54 |
| 2024 | 13 | 10-3 | +7.66u | -6.91u | 9-4 | 3-9-1 | 7.85 | 6.85 |
| 2023 | 13 | 7-6 | +2.44u | -2.39u | 8-5 | 4-9-0 | 7.96 | 7.92 |
| 2022 | 19 | 13-6 | +4.71u | -8.16u | 8-11 | 9-10-0 | 8.16 | 9.37 |
| 2021 | 19 | 8-11 | -2.17u | +2.52u | 11-8 | 11-8-0 | 8.76 | 8.74 |
| 2020 | 10 | 3-7 | -4.33u | +3.31u | 4-6 | 2-7-1 | 8.30 | 6.20 |
| 2019 | 19 | 10-9 | +0.04u | +0.53u | 8-11 | 6-12-1 | 8.89 | 8.32 |
| 2018 | 19 | 10-9 | -3.47u | +3.13u | 8-11 | 7-11-1 | 8.79 | 8.32 |
| 2017 | 19 | 12-7 | +1.51u | -1.14u | 12-7 | 5-13-1 | 9.18 | 7.84 |
| 2016 | 19 | 10-9 | -2.95u | +3.05u | 6-13 | 10-8-1 | 8.61 | 9.68 |
| All | 176 | 98-78 | +5.77u | -9.58u | 85-89 | 67-102-7 | 8.46 | 8.28 |
Guardians vs Twins by ballpark
| Venue | Games | Guardians record | Guardians ML units | Guardians run line | O/U/P | Avg total | Avg runs |
|---|---|---|---|---|---|---|---|
| At Guardians home park | 88 | 48-40 | -4.60u | 34-54 | 38-48-2 | 8.40 | 8.45 |
| At Twins home park | 88 | 50-38 | +10.37u | 51-35 | 29-54-5 | 8.52 | 8.11 |
Last 20 Guardians vs Twins games with closing odds
| Date | Game | Score | Winner | Close ML (away / home) | Total | O/U |
|---|---|---|---|---|---|---|
| Sep 13, 2026 | Guardians at Twins | 9-2 | Guardians | +104 / -126 | 8 | Over |
| Sep 12, 2026 | Guardians at Twins | 3-4 | Twins | -109 / -110 | 8.5 | Under |
| Sep 11, 2026 | Guardians at Twins | 5-2 | Guardians | -119 / -101 | 7.5 | Under |
| Jul 23, 2026 | Twins at Guardians | 3-1 | Twins | +123 / -149 | 7.5 | Under |
| Jul 22, 2026 | Twins at Guardians | 10-6 | Twins | +114 / -137 | 8 | Over |
| Jul 21, 2026 | Twins at Guardians | 2-5 | Guardians | +134 / -162 | 8 | Under |
| Jul 20, 2026 | Twins at Guardians | 4-13 | Guardians | -131 / +109 | 7.5 | Over |
| Jul 9, 2026 | Guardians at Twins | 5-2 | Guardians | -115 / -105 | 8.5 | Under |
| Jul 8, 2026 | Guardians at Twins | 5-6 | Twins | +108 / -131 | 8 | Over |
| Jul 7, 2026 | Guardians at Twins | 1-3 | Twins | -110 / -110 | 8.5 | Under |
| May 10, 2026 | Twins at Guardians | 5-4 | Twins | +135 / -163 | 7.5 | Over |
| May 9, 2026 | Twins at Guardians | 2-1 | Twins | +105 / -127 | 8 | Under |
| May 8, 2026 | Twins at Guardians | 4-6 | Guardians | +123 / -149 | 7.5 | Over |
| Sep 21, 2025 | Guardians at Twins | 2-6 | Twins | -120 / +105 | 8.5 | Under |
| Sep 20, 2025 | Guardians at Twins | 8-0 | Guardians | +105 / -115 | 8.5 | Under |
| Sep 20, 2025 | Guardians at Twins | 6-0 | Guardians | +105 / -115 | 8 | Under |
| Sep 19, 2025 | Guardians at Twins | 6-2 | Guardians | -105 / -115 | 8 | Push |
| Aug 3, 2025 | Twins at Guardians | 5-4 | Twins | +140 / -166 | 8 | Over |
| Aug 2, 2025 | Twins at Guardians | 4-5 | Guardians | +134 / -200 | 7.5 | Over |
| Aug 1, 2025 | Twins at Guardians | 2-3 | Guardians | +100 / -115 | 7.5 | Under |
Guardians vs Twins betting FAQ
Who leads the Guardians vs Twins series since 2016?
The Guardians, 98-78 in 176 regular season meetings.
Is it profitable to bet the Guardians against the Twins?
At closing moneylines the Guardians returned +5.77u (+3.3% ROI) over 176 games; the Twins returned -9.58u.
Do Guardians vs Twins games go over or under?
67 overs, 102 unders and 7 pushes against the closing total. The average total was 8.46 and the games averaged 8.28 runs.
How do the favorites do in Guardians vs Twins games?
The moneyline favorite won 91 of 172 meetings with a clear favorite (52.9%). Betting the favorite every time returned -16.85u; betting the underdog every time returned +13.27u.
When did the Guardians and Twins last play?
Sep 13, 2026: the Guardians won 9-2.
Methodology
Every regular season meeting since 2016 comes from the Bet Legend game database with its final score, closing moneylines, closing 1.5 run line and closing total, and each game is checked against ESPN's official final score; postseason meetings are not included. Moneyline units risk 1 unit at the close: a win at -150 pays +0.67u, a win at +130 pays +1.30u. Over and under compare total runs with the closing total, and an exact match is a push. A "clear favorite" is a game where the two closing moneylines differ. These are market results, not BetLegend picks.