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Guardians vs White Sox Betting History
The Guardians and White Sox have met 176 times in the regular season since 2016, and the Guardians lead the series 105-71. Betting the Guardians on the closing moneyline in every meeting returned +2.03u; betting the White Sox returned -13.90u. The games went 78-92-6 against the total, leaning under.
Updated October 1, 2026. Closing lines, regular season meetings only, 2016 to 2026. How these numbers are calculated.
Guardians vs White Sox betting summary
The moneyline favorite won 108 of 174 meetings with a clear favorite (62.1%). Betting the favorite every time returned -1.43u; betting the underdog every time returned -10.30u. The Guardians were 93-83 on the run line in the series.
Guardians vs White Sox results by season
Moneyline units risk 1 unit on that team in every meeting at the closing price.
| Season | Games | Guardians record | Guardians ML units | White Sox ML units | Guardians run line | O/U/P | Avg total | Avg runs |
|---|---|---|---|---|---|---|---|---|
| 2026 | 13 | 6-7 | -2.57u | +2.15u | 3-10 | 8-5-0 | 7.81 | 8.85 |
| 2025 | 13 | 11-2 | +4.73u | -8.71u | 8-5 | 4-9-0 | 8.12 | 6.77 |
| 2024 | 13 | 8-5 | -1.42u | -0.59u | 6-7 | 7-6-0 | 8.15 | 8.62 |
| 2023 | 13 | 5-8 | -3.33u | +2.92u | 5-8 | 3-9-1 | 8.65 | 6.92 |
| 2022 | 19 | 12-7 | +5.62u | -7.01u | 13-6 | 10-9-0 | 7.95 | 8.84 |
| 2021 | 19 | 9-10 | +0.65u | -1.43u | 11-8 | 10-9-0 | 7.58 | 8.16 |
| 2020 | 10 | 8-2 | +4.05u | -5.89u | 4-6 | 3-7-0 | 8.35 | 7.10 |
| 2019 | 19 | 8-11 | -6.88u | +11.73u | 8-11 | 10-9-0 | 8.79 | 8.79 |
| 2018 | 19 | 14-5 | +1.17u | -5.84u | 14-5 | 6-10-3 | 8.92 | 8.11 |
| 2017 | 19 | 13-6 | -0.91u | -0.68u | 11-8 | 7-11-1 | 8.55 | 7.63 |
| 2016 | 19 | 11-8 | +0.93u | -0.55u | 10-9 | 10-8-1 | 8.24 | 8.79 |
| All | 176 | 105-71 | +2.03u | -13.90u | 93-83 | 78-92-6 | 8.29 | 8.14 |
Guardians vs White Sox by ballpark
| Venue | Games | Guardians record | Guardians ML units | Guardians run line | O/U/P | Avg total | Avg runs |
|---|---|---|---|---|---|---|---|
| At Guardians home park | 88 | 56-32 | +3.19u | 43-45 | 40-46-2 | 8.23 | 8.09 |
| At White Sox home park | 88 | 49-39 | -1.16u | 50-38 | 38-46-4 | 8.35 | 8.18 |
Last 20 Guardians vs White Sox games with closing odds
| Date | Game | Score | Winner | Close ML (away / home) | Total | O/U |
|---|---|---|---|---|---|---|
| Sep 16, 2026 | White Sox at Guardians | 3-6 | Guardians | +137 / -166 | 7 | Over |
| Sep 15, 2026 | White Sox at Guardians | 6-7 | Guardians | +132 / -160 | 9 | Over |
| Sep 14, 2026 | White Sox at Guardians | 7-3 | White Sox | +152 / -184 | 7 | Over |
| Aug 9, 2026 | Guardians at White Sox | 3-5 | White Sox | -125 / +116 | 8.5 | Under |
| Aug 8, 2026 | Guardians at White Sox | 3-6 | White Sox | -123 / +114 | 7 | Over |
| Aug 7, 2026 | Guardians at White Sox | 8-2 | Guardians | -135 / +125 | 7.5 | Over |
| Jul 5, 2026 | White Sox at Guardians | 7-6 | White Sox | +122 / -147 | 8.5 | Over |
| Jul 4, 2026 | White Sox at Guardians | 3-1 | White Sox | +123 / -148 | 7.5 | Under |
| Jul 3, 2026 | White Sox at Guardians | 3-4 | Guardians | +114 / -137 | 8 | Under |
| Jul 2, 2026 | White Sox at Guardians | 5-6 | Guardians | -101 / -120 | 8.5 | Over |
| Jun 24, 2026 | Guardians at White Sox | 4-3 | Guardians | -111 / -109 | 8.5 | Under |
| Jun 23, 2026 | Guardians at White Sox | 1-2 | White Sox | -117 / -103 | 7 | Under |
| Jun 22, 2026 | Guardians at White Sox | 5-6 | White Sox | -110 / -110 | 7.5 | Over |
| Sep 14, 2025 | White Sox at Guardians | 2-3 | Guardians | -160 / -158 | 8 | Under |
| Sep 13, 2025 | White Sox at Guardians | 1-3 | Guardians | +148 / -164 | 8 | Under |
| Sep 12, 2025 | White Sox at Guardians | 0-4 | Guardians | +112 / -230 | 8 | Under |
| Aug 10, 2025 | Guardians at White Sox | 4-6 | White Sox | -138 / +119 | 8.5 | Over |
| Aug 9, 2025 | Guardians at White Sox | 3-1 | Guardians | -136 / +120 | 8.5 | Under |
| Aug 8, 2025 | Guardians at White Sox | 9-5 | Guardians | -166 / +142 | 8.5 | Over |
| Jul 13, 2025 | Guardians at White Sox | 6-5 | Guardians | -132 / +108 | 8.5 | Over |
Guardians vs White Sox betting FAQ
Who leads the Guardians vs White Sox series since 2016?
The Guardians, 105-71 in 176 regular season meetings.
Is it profitable to bet the Guardians against the White Sox?
At closing moneylines the Guardians returned +2.03u (+1.2% ROI) over 176 games; the White Sox returned -13.90u.
Do Guardians vs White Sox games go over or under?
78 overs, 92 unders and 6 pushes against the closing total. The average total was 8.29 and the games averaged 8.14 runs.
How do the favorites do in Guardians vs White Sox games?
The moneyline favorite won 108 of 174 meetings with a clear favorite (62.1%). Betting the favorite every time returned -1.43u; betting the underdog every time returned -10.30u.
When did the Guardians and White Sox last play?
Sep 16, 2026: the Guardians won 6-3.
Methodology
Every regular season meeting since 2016 comes from the Bet Legend game database with its final score, closing moneylines, closing 1.5 run line and closing total, and each game is checked against ESPN's official final score; postseason meetings are not included. Moneyline units risk 1 unit at the close: a win at -150 pays +0.67u, a win at +130 pays +1.30u. Over and under compare total runs with the closing total, and an exact match is a push. A "clear favorite" is a game where the two closing moneylines differ. These are market results, not BetLegend picks.