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Cardinals vs Cubs Betting History

The Cardinals and Cubs have met 173 times in the regular season since 2016, and the Cubs lead the series 88-85. Betting the Cardinals on the closing moneyline in every meeting returned -5.19u; betting the Cubs returned -8.53u. The games went 80-83-10 against the total, leaning under.

Updated October 1, 2026. Closing lines, regular season meetings only, 2016 to 2026. How these numbers are calculated.

Cardinals vs Cubs betting summary

85-88Cardinals vs Cubs, 2016 to 2026
-5.19uCardinals moneyline units
-8.53uCubs moneyline units
80-83-10over, under, push (49.1% overs)

The moneyline favorite won 96 of 171 meetings with a clear favorite (56.1%). Betting the favorite every time returned -8.13u; betting the underdog every time returned -5.50u. The Cardinals were 83-90 on the run line in the series.

Cardinals vs Cubs results by season

Moneyline units risk 1 unit on that team in every meeting at the closing price.

SeasonGamesCardinals recordCardinals ML unitsCubs ML unitsCardinals run lineO/U/PAvg totalAvg runs
2026137-6+2.76u-2.31u6-77-6-08.589.08
2025135-8-2.73u+0.20u5-88-5-08.819.23
2024137-6-0.07u-1.17u6-77-6-08.468.23
2023135-8-2.86u+2.82u6-74-6-39.388.92
20221913-6+2.27u-5.68u11-88-10-18.508.47
20211910-9-1.33u-1.18u7-1210-9-08.769.00
202074-3+1.27u-2.17u4-32-4-17.717.43
20191910-9+0.76u-0.46u9-109-10-08.928.05
20181910-9+0.98u-3.00u9-1010-7-28.5310.32
2017195-14-8.51u+6.39u10-97-10-28.327.89
2016199-10+2.29u-1.98u10-98-10-18.058.47
All17385-88-5.19u-8.53u83-9080-83-108.578.70

Cardinals vs Cubs by ballpark

VenueGamesCardinals recordCardinals ML unitsCardinals run lineO/U/PAvg totalAvg runs
At Cardinals home park8244-38-1.43u35-4731-46-58.518.00
At Cubs home park9141-50-3.76u48-4349-37-58.629.33

Last 20 Cardinals vs Cubs games with closing odds

DateGameScoreWinnerClose ML (away / home)TotalO/U
Aug 16, 2026Cardinals at Cubs11-4Cardinals+163 / -1769Over
Aug 15, 2026Cardinals at Cubs8-4Cardinals+168 / -1819Over
Aug 14, 2026Cardinals at Cubs0-3Cubs+168 / -1808Under
Jul 30, 2026Cubs at Cardinals4-2Cubs-106 / -1148.5Under
Jul 29, 2026Cubs at Cardinals2-3Cardinals-108 / -1128Under
Jul 28, 2026Cubs at Cardinals10-2Cubs-108 / -1129Over
Jul 27, 2026Cubs at Cardinals7-3Cubs-124 / +1039.5Over
Jul 5, 2026Cardinals at Cubs4-6Cubs+119 / -1438Over
Jul 4, 2026Cardinals at Cubs3-0Cardinals+146 / -1788Under
Jul 3, 2026Cardinals at Cubs17-1Cardinals+114 / -13710.5Over
May 31, 2026Cubs at Cardinals1-5Cardinals-101 / -1208.5Under
May 30, 2026Cubs at Cardinals6-1Cubs-131 / +1098Under
May 29, 2026Cubs at Cardinals5-6Cardinals-135 / +1127.5Over
Sep 28, 2025Cardinals at Cubs0-2Cubs+138 / -1468Under
Sep 27, 2025Cardinals at Cubs3-7Cubs+100 / -1749Over
Sep 26, 2025Cardinals at Cubs1-12Cubs+146 / -1749Over
Aug 10, 2025Cubs at Cardinals2-3Cardinals-123 / +1068Under
Aug 9, 2025Cubs at Cardinals9-1Cubs-138 / +1388.5Over
Aug 8, 2025Cubs at Cardinals0-5Cardinals-150 / +1188.5Under
Jul 6, 2025Cardinals at Cubs0-11Cubs+170 / -2007.5Over

Cardinals vs Cubs betting FAQ

Who leads the Cardinals vs Cubs series since 2016?

The Cubs, 88-85 in 173 regular season meetings.

Is it profitable to bet the Cardinals against the Cubs?

At closing moneylines the Cardinals returned -5.19u (-3.0% ROI) over 173 games; the Cubs returned -8.53u.

Do Cardinals vs Cubs games go over or under?

80 overs, 83 unders and 10 pushes against the closing total. The average total was 8.57 and the games averaged 8.70 runs.

How do the favorites do in Cardinals vs Cubs games?

The moneyline favorite won 96 of 171 meetings with a clear favorite (56.1%). Betting the favorite every time returned -8.13u; betting the underdog every time returned -5.50u.

When did the Cardinals and Cubs last play?

Aug 16, 2026: the Cardinals won 11-4.

Methodology

Every regular season meeting since 2016 comes from the Bet Legend game database with its final score, closing moneylines, closing 1.5 run line and closing total, and each game is checked against ESPN's official final score; postseason meetings are not included. Moneyline units risk 1 unit at the close: a win at -150 pays +0.67u, a win at +130 pays +1.30u. Over and under compare total runs with the closing total, and an exact match is a push. A "clear favorite" is a game where the two closing moneylines differ. These are market results, not BetLegend picks.