New York City FC midfielder Henrik Rydstrom in action during a 2026 MLS match, ahead of the club's Leagues Cup opener against Santos Laguna
New York City FC have not lost in three matches heading into their Leagues Cup opener against a Santos Laguna side on a three-game losing streak | Photo: Wikimedia Commons
Marquee Fixture
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Santos Laguna at NYCFC

Thursday, 7:30 PM ET | Sports Illustrated Stadium, Harrison, NJ

New York City FC have not lost in their previous three fixtures and are noticeably sharper at home, averaging 2.3 goals per 90 minutes at Sports Illustrated Stadium against just 1.0 on the road. That home-away split matters tonight, because the match is being played in Harrison.

Santos Laguna arrive in the opposite shape. They are winless in three Liga MX matches, including back-to-back losses without scoring against Atlas and Club America, and they sit at the bottom of the Liga MX table. On the road specifically, Santos have conceded three goals per game this season and failed to score in half of their away fixtures.

Market models give NYCFC roughly a 60 percent win probability against 18 percent for Santos and 22 percent for the draw, with a scoreless-through-one-goal NYCFC win the single most likely scoreline. Two clubs heading in opposite directions open the Leagues Cup for both of them tonight.

Eight Straight On The Road
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Cruz Azul at Philadelphia Union

Thursday, 8:00 PM ET | Subaru Park, Chester, PA

Cruz Azul are unbeaten in their previous eight road appearances, a run that survived right up until Sunday, when Atlante beat them to snap a fifteen-match unbeaten streak across every competition, their first loss of any kind since April. That defeat is fresh, but the road form underneath it has not actually broken yet.

Philadelphia counter with three straight MLS wins since their return from the World Cup break, seven goals scored across that stretch, genuine attacking form heading into the Leagues Cup. The complication is the venue: the Union have won just 33 percent of their nine matches at Subaru Park this year despite the form line, an odd split for a home side.

Market pricing has this close to even, Cruz Azul around 38 percent to win, Philadelphia 35 percent, and the draw at 27 percent, with Cruz Azul's road resume the main reason the Liga MX side is not a bigger underdog against an MLS club playing better football right now.

Lewandowski's First Goals
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Necaxa at Chicago Fire

Thursday, 8:30 PM ET | SeatGeek Stadium, Bridgeview, IL | CHI approx. -111

Chicago Fire won their last outing 2-1 over Charlotte, a match in which Robert Lewandowski scored both goals in his first appearance for the club after going behind early. That is the kind of result that changes how a market prices a team's next match, and Chicago is a modest favorite here.

Necaxa arrive having lost 3-1 at Toluca in their last Liga MX outing, a match that ended with the team down to nine men after conceding twice in the closing stages. That kind of collapse, more than the scoreline itself, is the concern the Fire's opponents will look to exploit.

Both clubs have been involved in high-event matches recently, and the model consensus favors Chicago at roughly 55 percent against 24 percent for Necaxa, with the draw around 21 percent. An over 2.5 goals line is viewed as playable given both sides' recent scoring and conceding habits.

Five Losses In Six
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Tijuana at Austin FC

Thursday, 9:00 PM ET | Q2 Stadium, Austin, TX

Austin FC have lost five of their last six matches without scoring in the two most recent, including a 1-0 defeat at Colorado Rapids. That is a rough entry point for a Leagues Cup opener, and the market has not been willing to make the home side more than a narrow favorite because of it.

Tijuana are the opposite story: a 2-1-0 start to their Liga MX season with wins over Tigres UANL and Leon, a scoreless draw against Atletico de San Luis, and an eight-game unbeaten run stretching back to last season. That form gap is closer to even than the home venue would normally suggest.

Model estimates put this near a genuine toss-up, Austin around 40 to 43 percent, Tijuana 32 to 34 percent and the draw taking the rest, one of the tightest true openers on Thursday's board.

Six Defeats In Ten
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Puebla at Portland Timbers

Thursday, 10:30 PM ET | Providence Park, Portland, OR | POR approx. -122

Portland enter on a four-match unbeaten streak, seven wins, three draws and eight defeats across 18 rounds, good for eighth in the MLS Western Conference. That form, combined with a home fixture in a stadium the club has traditionally defended well, makes them the clearest favorite on Thursday's board.

Puebla have lost six of their last ten matches and arrive with little momentum. The two clubs have never met before, so there is no head-to-head history for either side to lean on, only the current form line, which points heavily toward Portland.

Model projections give the Timbers roughly 59 to 67 percent to win outright, with Puebla in the 18 to 20 percent range and the draw filling the rest. Both teams to score and over 2.5 goals are both viewed as well above a coin flip.

One Goal Allowed All Tournament
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San Diego FC at Club America

Thursday, 10:00 PM ET | Estadio Azteca, Mexico City | AME approx. -180, SD approx. +425

Club America won the Liga MX Clausura last month, their tenth title in the tournament, and have two wins from their opening three matches this term while allowing just one goal all tournament. Hosting at Estadio Azteca, they are priced as the heaviest favorite on Thursday's board.

San Diego FC's away form is the entire story of the counterargument against them. The club has won only once in eight road matches this year, failed to score in 38 percent of those games, and kept a clean sheet in just 13 percent. They have also lost half of their 2026 road fixtures outright.

A trip to Mexico City against a club this stingy defensively is a difficult opener for any visiting side, and the market reflects it: America priced near -180, San Diego near +425, and the draw in the +310 to +330 range.

Board FAQ

How many matches are on the Leagues Cup board Thursday?
Six league-phase openers between MLS and Liga MX clubs: New York City FC vs Santos Laguna, Cruz Azul at Philadelphia Union, Chicago Fire vs Necaxa, Austin FC vs Tijuana, Portland Timbers vs Puebla, and Club America vs San Diego FC. The board opens at 7:30 PM ET and closes at 10:30 PM ET.
Why are Club America such big favorites over San Diego FC?
America won the Liga MX Clausura last month, their tenth title in the tournament, have two wins in their opening three league matches, and have allowed just one goal all term. San Diego have won only once in eight away matches this year and have lost half of their 2026 road games.
What is Cruz Azul's road record?
Cruz Azul are unbeaten in their previous eight road appearances, though they are coming off a surprise defeat to Atlante on Sunday that snapped a 15-match unbeaten run overall. Philadelphia Union have won just 33 percent of their matches at Subaru Park this year despite winning their last three MLS games.
Where is Club America playing and at what time?
At Estadio Azteca in Mexico City, with a 10:00 PM ET kickoff against San Diego FC, the final match to kick off on Thursday's board.
Which team enters on the worst recent run?
Santos Laguna, who are winless in three Liga MX matches with back-to-back defeats without scoring against Atlas and Club America, and have conceded three goals per game on the road this season.