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Marquee Matchup
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Dodgers at Cubs

Wednesday, 2:20 PM ET | Wrigley Field, Chicago, IL | CHC -120, total 10

Los Angeles has the best road record in baseball at 36-22, a plus 141 run differential and a 69-45 record, and the market has made it a +110 underdog. That is what a five-game losing streak and a 3-7 stretch will do, and it is also what happens when the pitching matchup runs backwards from the standings.

Eric Lauer takes the ball for the Dodgers with a 6.69 ERA and a 1.49 WHIP across six starts and 36.1 innings, having allowed eleven home runs in that short sample. His most recent outing was his best of the year, six shutout innings against Seattle on July 29 with one hit allowed, which is the thin reed Los Angeles is leaning on this afternoon. Behind him the offense is still the best in the sport by OPS at .769 with 146 home runs.

Chicago counters with Shota Imanaga, who has been the steadiest arm in this rotation all summer: 7-9 with a 3.67 ERA, a 1.07 WHIP, 119 strikeouts and 29 walks in 127.2 innings. He has given up two earned runs or fewer in each of his last three starts, including six shutout innings against Pittsburgh on July 25 and six and two-thirds against the Yankees on July 31. His one flaw is the long ball, 24 allowed, and Wrigley in August is where that flaw gets tested.

The Cubs are 65-49, 33-24 at home, and have scored 585 runs, the second most in baseball. The total of 10 is the highest number on the board outside Coors Field, which tells you what the market thinks of Lauer.

25 Homers In 76 Innings
Sportsnet

Blue Jays at Astros

Wednesday, 2:10 PM ET | Daikin Park, Houston, TX | HOU -210, total 8

Jameson Taillon has allowed 25 home runs in 76 innings. That is the highest rate of any starter on Wednesday's board by a distance, and it sits inside a 2-6 record with a 5.92 ERA and a 1.36 WHIP. His last time out he gave Pittsburgh four innings and seven earned runs on July 26.

Houston is the biggest favorite on the card at -210 and has earned some of it, going 8-2 over its last ten while leading the American League West at 59-56. The underlying numbers are less flattering: the Astros have been outscored by 24 runs on the season and carry a 4.61 staff ERA, the profile of a club winning close games rather than dominating them.

Hunter Brown is ten starts into his season with a 3.42 ERA, a .202 opponent average and one significant problem, 30 walks in 52.2 innings. He walked six Orioles on July 19 and then threw seven shutout innings with zero walks against the White Sox on July 25, which is the range. Toronto is 53-61 and has scored 444 runs, the fewest in the American League, so the walks may not cost him much here.

Two Years Between Pitches
Rangers Sports Network

Giants at Rangers

Wednesday, 2:35 PM ET | Globe Life Field, Arlington, TX | TEX -156, total 8.5

Cody Bradford makes his first major league start since 2024. He has spent all of 2026 on the 60-day injured list rehabbing left elbow surgery, and his five rehab starts between Double-A Frisco and Triple-A Round Rock produced 12 innings, 16 strikeouts and two walks. The last time he pitched in the majors he went 6-3 with a 3.54 ERA and a 1.01 WHIP over 13 starts.

San Francisco arrives at 48-66 and, more to the point, 22-39 on the road. The Giants are 4-12 away from home against left-handed starters, hit .246 with a .685 OPS against left-handed pitching, and are 2-12 on artificial turf. Globe Life Field has a turf surface. Matt Chapman, Harrison Bader and Casey Schmitt are all on the 10-day injured list.

Carson Whisenhunt is the other left-hander and the numbers are ugly: a 6.63 ERA, a 1.74 WHIP and 12 walks in 19 innings across four starts, a rate of 5.68 free passes per nine. His last outing lasted three and a third innings and cost six earned runs against San Diego. Texas is 29-26 at home with a 3.86 home staff ERA against 4.78 on the road, and the Rangers are 7-2 at home against lefty starters.

The 11.5 At Altitude
Regional

Rays at Rockies

Wednesday, 3:10 PM ET | Coors Field, Denver, CO | TB -158, total 11.5

An 11.5 is four and a half runs above the lowest number on the board and three above the median. Colorado has allowed 658 runs, the most in baseball, carries a 5.52 staff ERA and a 1.52 WHIP, and is 45-69. Coors Field does the rest of the arithmetic without being asked.

Nick Martinez is the curiosity here. He is 10-3 with a 2.77 ERA and a 1.10 WHIP, which is excellent, and he strikes out 5.04 batters per nine innings, which is the lowest rate of any starter working Wednesday. A contact pitcher at altitude is a specific kind of gamble, and his last outing was six innings and six earned runs against the White Sox on July 31.

Tampa Bay owns the sharpest home and road split in the sport at 41-18 at Tropicana Field and 26-28 everywhere else. The Rays are 67-46 overall and lead the American League East, and they are now at the least forgiving road venue that exists. Tomoyuki Sugano counters at 11-4 with a 4.47 ERA and 21 home runs allowed in 102.2 innings, though he has been sharp lately with three earned runs total across his last two starts.

145 Strikeouts, Three Wins
MASN

Angels at Orioles

Wednesday, 6:35 PM ET | Oriole Park at Camden Yards, Baltimore, MD | BAL -120, total 8

Reid Detmers has 145 strikeouts in 125 innings with a 4.03 ERA, a 1.10 WHIP and a .214 opponent average. His record is 3-7. That gap is the Angels season in one line: Los Angeles is 43-70, has been outscored by 76 runs, and is 2-8 over its last ten with an 18-37 road record.

Detmers has been excellent lately, allowing three earned runs total across his last three starts while striking out 22 in 16.1 innings, including nine against Houston on July 28. He walked one batter across those three outings combined.

Baltimore is 55-58 and a game and a half out of a wild card spot despite a minus 33 run differential, which is largely explained by a 10-17 record in one-run games. Trevor Rogers starts at 6-7 with a 4.27 ERA and has issued zero walks in each of his last two outings. The Orioles are 31-29 at Camden Yards.

The Closest Price On The Board
SNY

Mets at Guardians

Wednesday, 6:40 PM ET | Progressive Field, Cleveland, OH | NYM -102 / CLE -106, total 8

This is the tightest market of the day, the Mets at -102 and the Guardians at -106, and the two lineups explain why. New York has a .684 team OPS and Cleveland a .680, the two weakest offensive marks of any club playing Wednesday.

Tanner Bibee is 4-11 with a 3.81 ERA, a 1.15 WHIP and a .233 opponent average across 23 starts, one of the more misleading win-loss records in the sport. He has gone at least six innings in each of his last three, including seven and a third of two-run ball against Arizona on July 31. Cleveland has scored 448 runs all season, which is the actual reason for the eleven losses.

Christian Scott brings a 2.99 ERA and 85 strikeouts in 69.1 innings for the Mets, with 30 walks that keep the WHIP at 1.24. New York is 48-66, twelve games out of a wild card spot, and 10-20 in one-run games, the worst mark of any club on the board. Cleveland is 3-7 in its last ten.

Two Starters Above 5.40
Reds.TV

Athletics at Reds

Wednesday, 6:40 PM ET | Great American Ball Park, Cincinnati, OH | CIN -146, total 9.5

Both starters have an ERA above 5.40 and the game is in a bandbox, which is how a 9.5 gets posted. Jacob Lopez is 5-4 with a 5.79 ERA, a 1.67 WHIP and 42 walks in 70 innings, a rate of 5.40 per nine. Rhett Lowder is 3-7 with a 5.42 ERA and a 1.52 WHIP.

The Athletics are 45-68 and have lost six straight. They have allowed 646 runs, second most in baseball, carry a 5.42 staff ERA, and are 1-9 in their last ten. On the road they are 24-32, and the club is 14-29 against left-handed starters, which does not apply tonight but describes the depth of the problem.

Cincinnati is 54-58 and 27-31 at home, a mediocre record in a ballpark that has produced 145 team home runs. Lowder's last outing was his best in a month, six innings and two earned runs against Pittsburgh on July 30 with zero walks, sandwiched behind a July 18 disaster in which Colorado hit him for eleven hits and eight earned runs in two and a third.

610 Runs And Seven Straight Losses
NBCSP

Nationals at Phillies

Wednesday, 6:40 PM ET | Citizens Bank Park, Philadelphia, PA | PHI -184, total 9.5

Washington has scored 610 runs, more than any team in baseball, hit 166 home runs and posted a .765 OPS. Washington is also 55-60 and has lost seven in a row. The pitching staff has allowed 602 runs with a 4.78 ERA, which is the entire explanation.

Jake Irvin carries a 5.56 ERA and a 1.32 WHIP through 12 starts, and his last outing was five innings and five earned runs against Atlanta on July 30. The Nationals are a strange split team, 23-34 at home and 32-26 on the road, so a trip to Philadelphia is not automatically bad news for them.

Andrew Painter is 1-8 with a 6.72 ERA and a .304 opponent average, the highest of any starter on the board, and has allowed 15 home runs in 71 innings. His most recent start was six innings of two-run ball against Baltimore on July 31, easily his best of the season. Philadelphia is 61-53, has won four straight, and is 19-10 in one-run games.

Better On The Road Than At Home
Amazon Prime Video

Cardinals at Yankees

Wednesday, 7:05 PM ET | Yankee Stadium, Bronx, NY | NYY -154, total 8.5

New York is 27-24 at Yankee Stadium and 37-26 away from it, which is not how anyone drew this up in a park built for the roster. The Yankees have hit 164 home runs, most in baseball, and own the best staff ERA in the sport at 3.34 with a 1.19 WHIP.

Will Warren has been uneven and is trending the right way. He is 8-5 with a 4.14 ERA and a 1.36 WHIP, gave up six earned runs in three innings to Philadelphia on July 26, then answered with six and two-thirds of shutout ball and seven strikeouts against the Cubs on July 31 without walking anybody.

St. Louis is 56-58 and 3-7 in its last ten, but Andre Pallante has been the most reliable arm on the staff at 11-6 with a 3.72 ERA and 86 strikeouts in 118.2 innings. He threw seven shutout innings with eight strikeouts against Cincinnati on July 25. The Cardinals are 28-26 on the road against 28-32 at Busch Stadium, the second club on this board with backwards splits.

First Place Meets Six Straight
NESN

White Sox at Red Sox

Wednesday, 7:10 PM ET | Fenway Park, Boston, MA | BOS -126, total 8.5

Chicago leads the American League Central at 59-53 and is 34-21 at home against 25-32 on the road. Boston is 61-51, has won six in a row, is 8-2 over its last ten, and is 26-29 at Fenway Park against 35-22 on the road. Two clubs that both play better somewhere other than here are meeting here.

Sean Burke has quietly been one of the best starters in the league: 7-5 with a 3.04 ERA, a 1.10 WHIP, 140 strikeouts in 124.1 innings and a .220 opponent average. He struck out ten in each of his last two starts, six innings against Houston on July 25 and six shutout innings against the Yankees on July 30.

Sonny Gray is 13-2 with a 2.93 ERA and 98 strikeouts in 113.2 innings, and the record is doing some work there because his last two outings produced nine earned runs across twelve innings, including ten hits allowed in five against Toronto on July 25. Boston has allowed only 416 runs, fewest of any team playing Wednesday.

The Lowest Opponent Average
BravesVision

Marlins at Braves

Wednesday, 7:15 PM ET | Truist Park, Atlanta, GA | ATL -124, total 8.5

Eury Perez is holding hitters to a .201 average, the lowest mark of any starter on Wednesday's board, with a 3.44 ERA, a 1.10 WHIP and 112 strikeouts in 104.2 innings. He gave Milwaukee six shutout innings with nine strikeouts on July 19 and has allowed four earned runs total across his last three starts.

Atlanta is 68-45, has won six in a row and is 37-20 at Truist Park, the second-best home record in baseball behind Tampa Bay. The Braves have scored 553 runs and hit 152 home runs with a 3.66 staff ERA, a complete team profile with no obvious soft spot.

Miami is 58-56 and the split is stark: 34-23 at loanDepot Park and 24-33 on the road. Bryce Elder starts for Atlanta at 7-6 with a 3.84 ERA and 19 home runs allowed in 119.2 innings, which is the one number Miami can work with. The Marlins are 12-17 against right-handed starters this season, so the platoon math does not favor them.

Sixteen Shutout Innings
Royals.TV

Twins at Royals

Wednesday, 7:40 PM ET | Kauffman Stadium, Kansas City, MO | KC -114, total 8.5

Noah Cameron has thrown fifteen consecutive shutout innings across his last two starts, seven against Detroit on July 24 and eight against Minnesota on July 30, allowing three hits total in the second of them. His season line is 5-8 with a 4.59 ERA, so the recent run is a genuine change rather than a continuation.

Dean Kremer has gone the other way. He is 1-4 with a 6.50 ERA and twelve home runs allowed in 36 innings over seven starts, and his last outing was four innings and eight earned runs against Detroit on July 28. Minnesota is 56-58 and has lost three straight.

Kansas City is 47-67 and the road half of that is brutal, 20-40 away from Kauffman Stadium against 27-27 at home. The Royals are also 9-23 against left-handed starters, the worst such mark on the board, which does not apply against the right-handed Kremer. That is most of why a 47-win club is favored.

The Lowest Total On The Board
ESPN

Pirates at Brewers

Wednesday, 7:40 PM ET | American Family Field, Milwaukee, WI | MIL -122, total 7

Seven is the lowest total anywhere on this board, four and a half runs below the 11.5 at Coors Field. Paul Skenes brings 156 strikeouts and 32 walks in 124.2 innings, a rate of 11.26 per nine, with a 1.11 WHIP and a .230 opponent average across 23 starts. Milwaukee's staff is second in baseball at a 3.47 ERA and runs a 3.11 ERA inside this building.

The Brewers are 70-43, the best record in the sport, and 2-6 against Pittsburgh this season. The Pirates won two of three here in April, swept a July series at PNC Park including a 14-5 afternoon, and took Monday's opener 4-3 before Milwaukee answered 4-2 on Tuesday.

Kyle Harrison starts for Milwaukee and has not pitched since July 8, having spent twenty-eight days on the 15-day injured list with left forearm tightness. His season line is 8-2 with a 3.01 ERA, a 1.08 WHIP and 101 strikeouts in 83.2 innings. Pittsburgh is 10-23 against left-handed starters and hits .243 with a .704 OPS on the road, and it is without Oneil Cruz and Ryan O'Hearn. This matchup gets a full breakdown on the featured game page.

0.99 Against 6.53
Regional

Padres at Diamondbacks

Wednesday, 9:40 PM ET | Chase Field, Phoenix, AZ | SD -118, total 8.5

Casey Mize owns the lowest WHIP of any starter on the board at 0.99, with a 2.70 ERA, 85 strikeouts and 19 walks in 86.2 innings and only five home runs allowed. He has walked two batters total across his last three outings.

Mitch Bratt is at the other end of the same category. Five starts, 20.2 innings, a 5.23 ERA and a 1.84 WHIP built on 15 walks, a rate of 6.53 per nine. He walked five Nationals on July 25 and four Guardians on July 31, though the second of those still produced five innings and one earned run.

Arizona is 60-54 with a run differential of plus one, the flattest profile in baseball, and is 18-9 against left-handed starters against 42-45 versus right-handers. San Diego is 59-55 and 8-2 over its last ten, one game out of a wild card spot, and 32-25 at home against 27-30 on the road.

An Opener On The West Coast
Detroit SportsNet

Tigers at Mariners

Wednesday, 9:40 PM ET | T-Mobile Park, Seattle, WA | SEA -148, total 7.5

Detroit is listing Drew Anderson, who has made two starts all season inside 63.2 innings of work, with a 4.24 ERA and 78 strikeouts. His last three appearances lasted one and two-thirds, one and a third, and one and a third innings. This is an opener, and the Tigers bullpen is being asked to cover most of a game in the Pacific time zone.

That is a bolder plan than it sounds because Detroit is playing well. The Tigers are 55-58 but have won four straight and six of ten, and the staff ERA of 3.56 is better than Seattle's 3.78. They are also 25-31 on the road.

Bryan Woo starts for Seattle at 7-8 with a 4.56 ERA and a 1.15 WHIP, and the peripherals are much better than the ERA: 122 strikeouts against 26 walks in 120.1 innings, a rate of 1.94 free passes per nine. His last two outings each cost five earned runs. Seattle is 32-25 at home and 23-34 away, and the 7.5 here is the second lowest number on the board.

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