Game 1
FS1

#8 Iowa State @ Colorado

Thursday, 7:00 PM ET | CU Events Center, Boulder, CO
Spread
ISU -17.5 (-110)
Moneyline
ISU -1400 / COL +750
Total
O/U 152.5

This is what Big 12 dominance looks like. Iowa State comes into Boulder as 17.5-point road favorites, and that number tells you everything about the talent disparity in this conference matchup. The Cyclones at 17-2 (7-1 Big 12) have been one of the most complete teams in college basketball this season, ranking in the top 15 nationally in both offensive and defensive efficiency according to KenPom. T.J. Otzelberger has built something special in Ames, and his team's ability to defend, share the ball, and close games has made them a legitimate Final Four threat.

Colorado sits at 13-7 (3-5 Big 12) and has found Big 12 play to be exactly as brutal as advertised. Tad Boyle's group has been competitive at home, but facing a team of Iowa State's caliber is a completely different animal. The Buffaloes have struggled to find consistent scoring, and their defense, while improved, will be pushed to its limits against a Cyclones offense that moves the ball beautifully and can hurt you from all three levels. The altitude in Boulder provides some home court advantage, but it's unlikely to overcome an 17.5-point talent differential.

The 152.5 total suggests a moderately-paced contest, which is right in Iowa State's wheelhouse. The Cyclones don't run teams out of the gym with pace; they suffocate you with defense and execute precisely on offense. Colorado's best chance to cover involves slowing the game down further and hoping for some home-shooting magic, but realistically, Iowa State has the defensive versatility to adjust to any style. This spread is large, but it reflects the reality of where these programs stand in the Big 12 hierarchy. Iowa State is simply operating on a different level.

Game 2
FS1

#9 Illinois @ Washington

Thursday, 9:00 PM ET | Alaska Airlines Arena, Seattle, WA
Spread
ILL -12.5 (-110)
Moneyline
ILL -700 / WASH +475
Total
O/U 153.5

Illinois makes the cross-country trip to Seattle as heavy favorites, and the Fighting Illini at 17-3 (7-2 Big Ten) have been everything Brad Underwood could have hoped for this season. This is a team that combines elite athleticism with improved defensive consistency, and their ball movement has been a revelation compared to previous years. Illinois ranks top 10 nationally in adjusted offensive efficiency, and they've proven they can win games in multiple ways, whether it's through high-tempo transition basketball or grinding half-court execution.

Washington at 10-10 (3-6 Big Ten) is still adjusting to life in their new conference, and it hasn't been kind. The Huskies have shown flashes of competitiveness, but the depth of Big Ten talent has exposed their roster limitations. Danny Sprinkle's group needs to find a breakthrough win to build momentum, but facing a Top 10 opponent on the road to their Big Ten confidence is a tall order. Washington will need to control tempo, limit turnovers, and hit an abnormally high percentage of three-pointers to have any chance of keeping this close.

The 153.5 total is intriguing given Illinois's offensive firepower, but don't expect a shootout. Illinois has tightened defensively this season, and they're comfortable winning games in the 70s rather than needing to score 90. Washington's best-case scenario involves slowing the game down and hoping Illinois goes cold from three, but the Illini have too many weapons to be completely shut down. The 12.5-point spread reflects the significant talent gap, but also accounts for the travel and time zone challenges that come with a Big Ten coast-to-coast trip. Illinois should handle business, but road games in the Pac-12 footprint always carry some inherent variance.

Game 3
Peacock

Northwestern @ Penn State

Thursday, 8:00 PM ET | Bryce Jordan Center, University Park, PA
Spread
NW -8.5 (-110)
Moneyline
NW -350 / PSU +275
Total
O/U 149.5

Northwestern heads to Happy Valley as road favorites in a Big Ten matchup between two teams going in opposite directions. The Wildcats at 15-5 (6-3 Big Ten) have been one of the conference's pleasant surprises this season, with Chris Collins continuing to build on the program's recent success. Northwestern's defense has been the story, ranking in the top 30 nationally in defensive efficiency, and their ability to lock down opponents in half-court settings has been the foundation of their success. They're not flashy, but they're effective and well-coached.

Penn State at 10-10 (2-7 Big Ten) has struggled mightily in conference play, and Mike Rhoades' first season in State College has been a tough transition. The Nittany Lions have the talent to be competitive, but consistency has been elusive. Their offense has sputtered at times, and their defense hasn't been able to bail them out like Northwestern's does. The Bryce Jordan Center can be a difficult place to play when the crowd is engaged, but Penn State will need a complete performance to compete with a Northwestern team that knows how to grind out road wins.

The 149.5 total is the lowest on tonight's slate, and it perfectly captures what this game should look like. Northwestern wants to play in the 60s, controlling tempo and forcing opponents into uncomfortable half-court possessions. Penn State would prefer more pace, but they don't have the defensive consistency to match Northwestern's physicality. This game will likely be decided in the final five minutes, with Northwestern's late-game execution giving them the edge. The 8.5-point spread is significant for a road game, but Northwestern has earned that respect with their defensive identity.

Game 4
ESPN2

Memphis @ Florida Atlantic

Thursday, 8:00 PM ET | Eleanor R. Baldwin Arena, Boca Raton, FL
Spread
MEM -2.5 (-110)
Moneyline
MEM -140 / FAU +120
Total
O/U 151.5

This is the tightest game on the board, and for good reason. Memphis and Florida Atlantic are evenly matched AAC opponents with conference positioning on the line. The Tigers at 14-6 (5-3 AAC) have been inconsistent but talented, with Penny Hardaway's group showing flashes of brilliance mixed with puzzling losses. Memphis has the athleticism to compete with anyone in the country, but their execution in close games has been hit or miss. They're favored by just 2.5 points on the road, which tells you how much respect FAU has earned at home.

Florida Atlantic at 13-7 (5-2 AAC) has been rock solid in Boca Raton, and the Owls have proven they belong in the upper tier of the AAC. Dusty May built something special here before leaving for Michigan, and the current staff has maintained that defensive identity and physical style of play. FAU won't back down from Memphis's athleticism, and their home court has been a significant advantage this season. The Owls have wins over quality opponents in this building, and they'll view this as a statement opportunity against a bigger-name program.

The 151.5 total suggests a moderately-paced game, which is typical for AAC action. Both teams can score, but defense and physicality will likely determine the outcome. Memphis needs to control the glass and avoid turnovers against FAU's pressure defense. The Owls need to execute in half-court sets and not let Memphis turn this into a track meet. This is the kind of AAC matchup that won't get national headlines but features two teams fighting for NCAA Tournament positioning. Expect a tight, physical contest that could go either way in the final minutes.