D-backs @ Orioles
Wednesday, 12:35 PM ET
The series finale at Camden Yards kicks off with an early afternoon start, and the pitching matchup is fascinating for very different reasons. Eduardo Rodriguez has been lights-out to open 2026, carrying a 1-0 record with a sparkling 0.50 ERA and a 1.00 WHIP while racking up 11 strikeouts. Rodriguez has always had the talent to be a frontline starter, and when his changeup is working in tandem with the fastball, he can make lineups look foolish for entire outings. The D-backs are getting genuinely elite work from the lefty, and the +135 moneyline suggests the market is still catching up to how good he's been.
Kyle Bradish returns from Tommy John surgery for Baltimore, and his early-season numbers have been encouraging: a 1-1 record with a 2.53 ERA, a 1.03 WHIP, and 47 strikeouts that show the stuff is still there. Bradish's fastball-slider combination was devastating before the injury, and the fact that he's already generating this many punchouts tells you the arm talent hasn't diminished. The -163 moneyline on the Orioles is built on Bradish's upside and the home environment, but there's an inherent risk in backing a pitcher still working his way back to full strength against a lineup as dangerous as Arizona's.
Baltimore enters this one without Adley Rutschman, who's on the 10-day IL with an ankle injury, and Ryan Mountcastle is also sidelined with a foot problem. Those are two significant bats missing from a lineup that was already trying to find its footing in the early going. The Orioles' depth will be tested, and against a pitcher as sharp as Rodriguez has been, every lineup spot matters. Arizona's offense has been potent when the middle of the order gets going, and if they can get to Bradish early while he's still rebuilding his pitch count endurance, the D-backs could put this game out of reach before the later innings.
The 9 total is one of the higher numbers on the board, and Camden Yards has always been a place where offense can explode in a hurry. The short porch in right field rewards left-handed power, and both lineups have hitters who can take advantage of the dimensions. Rodriguez's ability to limit damage through swing-and-miss stuff could keep the D-backs' side of the scoreboard manageable, but Bradish is still finding the balance between attacking the zone aggressively and protecting himself against hard contact. This early start could play into Arizona's hands if they can jump on Bradish in the first couple of innings before he settles in.